OBJECTIVE：To inve stigate the current situation of clinical pharmacists ’job stress and presenteeism behavior in tertiary hospitals of China and study their correlation. METHODS ：Using the Brief Job Stress Questionnaire （BJSQ）and the presenteeism behavior individual questionnaire ，a survey of 623 clinical pharmacists in 311 tertiary hospitals from 31 provinces in China was conducted ；by establishing Logistic model between job stress ，its various dimensions （job demand ，job control ， support）and presenteeism behavior ，the correlation analysis was performed for their survey results. RESULTS ：The average job pressure of the interviewed clinical pharmacists was 36.75 points；the probability of presenteeism behavior was 20.38％. Logistic regression model analysis results showed that job stress and its two dimensions （job demand ，job control ）had a significant positive correlation with presenteeism behavior （P＜0.05）. CONCLUSIONS ：The job stress of clinical pharmacists in tertiary hospitals in my country is relatively high ，which is also the main reason for their presenteeism behavior. Job stress can be reduced （such as increasing the staffing appropriately ，providing reasonable rest time ，improving the job substitution of clinical pharmacists ）to reduce the prevalence of presenteeism behavior.