OBJECTIVE： To establish a method for simultaneous determination of the contents of gallic acid， jasminoidin， albiflorin， paeoniflorin， danshinolic acid B， paeonol and tanshinone ⅡA in Gankangfu water pill. METHODS： HPLC method with DAD was adopted. The determination was performed on Agilent ZORBAX SB-C18 column with mobile phase A consisted of acetonitrile and mobile phase B consisted of 0.1％ phosphate solution （gradient elution） at the flow rate of 1.0 mL/min. The detection wavelengths were set at 267 nm （gallic acid）， 235 nm （jasminoidin， albiflorin， paeoniflorin）， 286 nm （danshinolic acid B）， 274 nm （paeonol） and 270 nm （tanshinone ⅡA） . The column temperature was set at 30 ℃ and sample size was 10 μL. RESULTS： The linear range of gallic acid， jasminoidin， albiflorin， paeoniflorin， danshinolic acid B， paeonol and tanshinone ⅡA were 4.09-51.17 μg/mL （r＝0.999 5）， 8.35-104.35 μg/mL （r＝0.999 1）， 7.78-97.25 μg/mL （r＝0.999 9）， 7.56-94.54 μg/mL （r＝0.999 3）， 16.70-208.80 μg/mL （r＝0.999 5）， 3.46-43.20 μg/mL （r＝0.999 7）， 23.13-289.10 μg/mL （r＝0.999 9）， respectively. The detection limits were 0.09， 0.15， 0.13， 0.12， 0.16， 0.04 and 0.24 μg/mL； quantitative limits were 0.26， 0.52， 0.48， 0.47， 0.88， 0.18 and 0.98 μg/mL， respectively. The average recovery rates were 91.83％， 96.11％， 96.83％， 95.82％， 96.93％， 93.95％ and 94.79％， respectively （n＝6）. RSDs of precision test were not more than 1.00％ （n＝6）. RSDs of stability test were not more than 0.96％ within 48 h （n＝6）， and RSDs of repeatability test were than 0.99％ （n＝6）. CONCLUSIONS： The method is accurate and reliable， and can be used for content determination of above 7 components in Gankangfu water pill.