OBJECTIVE： To systematically review the efficacy of modified Gualou xiebai banxia （GLXBBX） decoction combined with chemical drugs versus chemical drugs alone in the treatment of stable angina pectoris （SAP） of coronary heart disease， and to provide evidence-based reference for clinical treatment. METHODS： Retrieved from PubMed， EMBase， Cochrane library， CJFD， VIP and Wanfang database， RCTs about therapeutic efficacies of GLXBBX decoction combined with chemical drugs （experimental group） versus chemical drugs alone （control group） in the treatment of SAP were collected. Meta-analysis was conducted by using Rev Man 5.3 statistical software after data extraction of clinical studies met inclusion criteria and quality evaluation with Cochrane 5.1.0 quality evaluation tool （total response rate of angina pectoris efficacy and ECG improvement， blood lipid level）. RESULTS： There were totally 10 RCTs， involving 820 patients. The results of Meta-analysis showed that the total response rate of angina pectoris efficacy [RR＝1.25， 95％CI （1.17，1.35）， P＜0.001]， total response rate of ECG improvement [RR＝1.35， 95％CI（1.19，1.53）， P＜0.001]， decrease LDL improvement [MD＝－0.45， 95％CI （－0.71， －0.19）， P＜0.001] in experimental group were significantly better than control group. There was no significant ADR. CONCLUSIONS： For SAP of coronary heart disease， modified GLXBBX decoction combined with chemical drugs is better than chemical drugs alone in total response rate of angina pectoris efficacy，total response rate of ECG improvement，and decrease LDL improvement.