OBJECTIVE： To provide reference for the clinical pharmacists to determine their work orientation， and improve their work mode and pharmaceutical care level. METHODS： The questionnaire survey was conducted among doctors， nurses， patients and pharmacists from 65 third grade class A hospitals of 18 provinces （regions， cities） in China. The collected data were analyzed statistically and suggestions were presented. RESULTS： Totally 3 840 questionnaires were sent out， 3 045 were effectively received with a recovery of 79.30％[involving 56 third grade class A hospitals of 17 provinces （regions， cities）]. Of 3 045 valid questionnaires， 1 001 questionnaires were filled out by the doctors and nurses， 1 013 questionnaires were filled by the pharmacists and 1 031 questionnaires were filled out by the patients. 88.45％ of the survey doctors and nurses thought that clinical pharmacists were needed in their wards. The major clinical pharmaceutical care they needed were the participation of clinical pharmacists in the clinical ward round， patients management， difficult case discussions， consultation （77.32％）， etc. 64.54％ of the survey doctors and nurses thought that clinical pharmacists could participate the clinical work and solve some simple medicine-related problems， and 27.17％ of the survey doctors and nurses thought that clinical pharmacists could resolve clinical medicine-related problems. 14.59％ of the survey doctors and nurses believed that clinical pharmacists lacked clinical thinking and could not communicate with medical staff. The most common problems the survey medical staff met were as follows： ADR （78.02％）， usage and dosage （72.83％）， contraindications （72.63％）， drug indication （63.14％） and solvent selection （61.74％）， etc. As regards the ratio of working time which clinical pharmacists spent on their clinical work， over 50％（35.55％） and 30％（23.46％） were most chosen by the survey pharmacists， while 13.19％ of the survey pharmacists thought clinical pharmacists almost did not participate in clinical work. The survey pharmacists thought that there were some deficiencies in the knowledge structure of clinical pharmacists， such as clinical medical science and therapeutics （92.50％）， communication  skills （47.19％） ， professional knowledge of pharmacy（46.10％）， etc. 87.90％ of the survey patients were willing to accept the medication guidance provided by clinical pharmacists. The services they required were as follows：medication guidance（79.92％）， observation and discovery of medication problem（71.00％）， etc. CONCLUSIONS： Medical staff and patients have demands in many ways associated with clinical work and rational drug use provided by clinical pharmacists， while the clinical pharmacists have yet not reached the demands of medical staff and patients in regard to their evaluation. It is suggested that the clinical pharmacists should ascertain their work orientation， improve their work mode， participate the clinical work in full-time， complete their knowledge structure and ascent their pharmaceutical service level.