OBJECTIVE： To provide reference and basis for strengthening the drug quality supervision of medical institutions. METHODS： The problems about the drug quality supervision of the medical institutions were analyzed from the angle of legislation. Countermeasures for strengthening drug quality supervision of medical institutions in China as well as legislative suggestions on improving drug quality supervision of medical institutions in China were put forward. RESULTS & CONCLUSIONS： At pre- sent， the existing problems about drug quality supervision in medical institutions include that pharmacy setting lack mandatory standards； routine drug quality supervision is mainly the formal regulation； the punishment of drug related illegal behavior in medical institutions is too light， etc. To strengthen drug quality supervision of medical institutions in China， it is suggested that the government should establish the mandatory standards for medical institution pharmacy setting， add administrative inspections， and formulate Good Using Practice applicable to the whole country. When perfecting the law of drug quality supervision in medical institutions in China， relevant provisions may be added in The Drug Administration Law of the PRC， Regulations for the Implementation of Drug Administration Law， and the subordinate laws and regulations of Management Regulation of Medical Institutions so as to strengthen drug quality supervision of medical institutions.