OBJECTIVE： To establish GC-MS fingerprints of liposoluble constituents from Danqi soft capsule. METHODS： GC-MS method was adopted. GC chromatogram column was DB-5 ms capillary column with high purity helium  （99.999％） as carrier gas at the flow rate of 1.0 mL/min， with temperature programming. The injector temperature was 250 ℃.The sample size was 1 μL. The shunt ratio was 1∶40， with distributary injection. Ionization mode was as follows as electron bombardment ion source， ion source temperature of 280 ℃， injector temperature of 300 ℃， electronic energy of 70 eV， solvent delay time of 3 min， mass charge ratio （m/z） of 50-550. Using ethyl palmitate as reference， MS spectrums of 11 batches of samples were determined. Similarity evaluation was conducted by using TCM Fingerprint Chromatogram Similarity Evaluation System （2004 A edition） to determine common peak. The common peaks were determined by LC Solution 2 workstation standard mass spectrometry Library  （NIST05.LIB or NIST05s.LIB）. RESULTS： The similarity of 11 batches of samples was higher than 0.90. After validation， GC-MS chromatograms of 11 batches of samples were in good agreement with control fingerprint. There were 49 common peaks in GC-MS chromatogram， and 38 chemical constituents were identified， accounting for 94.94％ of total peak areas. CONCLUSIONS： Established fingerprint can provide evidence for quality evaluation of Danqi soft capsule.