OBJECTIVE: To provide reference for the better development of internet pharmaceutical service of hospital pharmacists. METHODS: The questionnaire investigation was carried out on the cognition of pharmacists to internet pharmaceutical service in 9 third grade class A hospitals. The survey data were analyzed statistically. RESULTS: A total of 600 questionnaires were distributed and 527 questionnaires were collected with recovery rate of 87.8%. Among them, there were 499 valid questionnaires with effective rate of 94.7%. The most selected internet pharmaceutical service contents were medication consultation (94.4%) and medication education (91.6%). 93.0% considered that internet pharmaceutical service were worthy or very worthy of promotion. The most concerned issues about internet pharmaceutical service were technical problems (58.5%) and legal liability (55.9%). 57.1% of the surveyed pharmacists considered that they were totally or possibly capable of performing internet pharmaceutical care; 37.9% didn’t get in touch with internet pharmaceutical care and were not clear about it. The most important qualifications of pharmacists who provided internet pharmaceutical service were rank of pharmacist’s title (67.9%) and working experience (67.7%). It was considered that the most effective measures to ensure the quality of internet pharmaceutical care were regular pharmaceutical service training (74.3%) and proportionally sampling the quality of pharmaceutical service consultation (67.5%). CONCLUSIONS: Internet pharmaceutical service may become a new direction of the development of pharmaceutical service under new medical reform. The development of internet pharmaceutical service requires perfect laws and regulations, and pharmacist team with high professional level.