OBJECTIVE： To shorten the turnover days of hospital drug inventory， reduce the cost of drug inventory and improve the level of hospital drug inventory management. METHODS： The data of 65 kinds of antitumor drugs and its adjuvant drugs during Jan. 1st， 2016-Dec. 31st， 2016 were collected from hospital information system （HIS） of our hospital， such as price， inventory to classify by using ABC classification method. According to demanded quantity of class A drugs in the secondary drug storage， the amount purchased of upper and lower limitation of class A drugs could be calculated. The data of class C drugs were analyzed one by one to determine the “temporary use” drug directory. The turnover days of class A drugs and the inventory cost of class C drugs were counted before and after classification management. RESULTS： There were 10 class A drugs， accounting for 15.38％ of total types and 78.27％ of total consumption sum； the turnover days of pharmacy inventory decreased from （43.96±19.04） d to （13.64±8.02） d by adopting the principle of purchasing in small quantity by several times. There were 10 “temporary use” drugs of class C drugs， accounting for 26.32％ of total types， 270 thousand yuan inventory cost saved each year. CONCLUSIONS： Hierarchical management of hospital drug inventory by ABC classification can effectively optimize the inventory types and amount， and provide definite evidence for “temporary use” drugs so as to shorten turnover days of pharmacy inventory and recue the cost of pharmacy inventory.