OBJECTIVE： To strengthen the comprehensive control of drug dispensing errors in our hospitals and ensure the medication safety of patients. METHODS： The steps and related contents for drug dispensing errors implemented in our hospital based on hazard analysis and critical control point method （HACCP） were introduced， and the management effects were evaluated by comparing the dispensing error before （2015） and after management （2016）. RESULTS： Starting from establishing groups， our hospital drew flow chart of drug dispensing， and plans [including hazard analysis， determining critical control points （CCP）， establishing critical limits （CL）， monitoring system， correlative measures， confirming process and quality records] were developed based on HACCP principle. And 4 CCPs were identified， naming reviewing prescription， dispensing drugs， writing drug bags or pasting labels and delivering the drugs to patients. Related measures were implemented， which had achieved the effective management and control for drug dispensing. Compared with before implementing HACCP， the drug dispensing error rate in our hospital was declined by 84.73％ （0.753‰ vs. 0.115‰）. CONCLUSIONS： Scientifically applying HACCP for drug dispensing in hospital can effectively control the drug error risk and promote the medication safety of patients.