OBJECTIVE： To investigate the role of nutrition support pharmacists in individualized nutritional treatment. METHODS： The nutrition support pharmacists participated in the treatment for a patient with esophageal cancer. The patient received radiotherapy instead according the progression of disease. Nutrition support pharmacists suggested that parenteral and enteral nutrition instead of previous nutrition support plan according to disease condition， the requirements of peripheral venous infusion， economic condition. Parenteral nutrition used peripheral venous infusion of “all in one” nutrient solution [containing 5％ Glucose injection 250 mL， 50％ Glucose injection 100 mL， 20％ Medium and long chain fat emulsion injection （C6-24） 250 mL， 8.5％ Compound amino acid injection （18AA-Ⅱ） 250 mL， 10％ Potassium chloride injection 10 mL， Water-soluble vitamin for injection 1 branch， Fat-soluble vitamin injection （Ⅱ） 10 mL， osmotic pressure 750 mOsm/L] 870 mL， once a day. Enteral nutrition was Enteral nutritional powder 55.8 g mixed with warm water 250 mL， po， 2-3 times a day. According to physical condition and food intake， it was suggested to increase the frequency of Enteral nutritional powder to 4-5 times a day， gradually discontinued “all in one” parenteral nutrition. RESULTS： Physicians adopted the suggestions of nutrition support pharmacists； the patient had a good nutritional status and completed 17 radiotherapy successfully， and discharged from hospital on 37th day. CONCLUSIONS： Nutrition support pharmacists as a member of clinical treatment team play their own pharmaceutical advantages to optimize and adjust the nutritional program in respects of nutrition support way， infusion mode and nutrient solution ratio from the actual needs and aspirations of patients. Under the premise of following the objective rules of medical practice， the nutrition support pharmacists fully respected the individual wishes of patients to lay a foundation for improving the nutritional status and ensuring the successful completion of anti-tumor treatment.