OBJECTIVE： To improve teaching quality of the course of Medicinal Chemistry. METHODS： On the basis of understanding the nature， characteristics and main existing teaching problems of the course of Medicinal Chemistry， concept map method was used to reveal the regularities of the course contents in order to organize classroom teaching. RESULTS： The regularities of the intricate abstract course contents of Medicinal Chemistry， including regularities of some specific drugs and interrelationships among drugs， were intuitively reflected by concept map method. In daily teaching activities， under teacher’s guidance， students autonomously discovered course knowledge by drawing concept map. Different students had different learning results， but on the whole， autonomous learning ability and learning efficiency of the students were improved. CONCLUSIONS： The concept map method is effective method for improving the teaching quality of Medicinal Chemistry.