OBJECTIVE： To prepare Frovatriptan succinate film-coated tablet， and investigate its in vitro dissolution behavior. METHODS： Using lactose monohydrate， microcrystalline cellulose， dioxide， silica， sodium carboxymethyl starch and magnesium stearate as accessories， Frovatriptan succinate tablet was prepared. Using opadry premix spray-coating liquid， Frovatriptan succinate film-coated tablet was prepared. Single factor test was used， using moisture， angle of repose， rigidity， friability， disintegration time and dissolution rate as indexes， to screen the formulation； using dissolution degree as index， coating material dosage was screened. The dissolution curves in vitro of self-made tablets and imported tablets in water， 0.1 mol/L HCL， pH of 5.5， 6.8 phosphate buffer solutions were compared. RESULTS： The optimal formulation of Frovatriptan succinate uncoated tablet was as follow as frovatriptan succinate 3.91 mg， lactose monohydrate 99.18 mg， microcrystalline cellulose 33.06 mg， magnesium stearate 1.40 mg， sodium carboxymethyl starch 1.05 mg， silica 1.40 mg； optimal coating weighed quality was 2.0％-4.0％. In the 4 mediums， the dissolution behavior of self-made tablets and imported tablets were similar. CONCLUSIONS： Frovatriptan succinate film-coated tablet is prepared successfully， and its in vitro dissolution behavior is similar to the imported preparations.