OBJECTIVE： To establish the method for contents determination of catechins active components in lipid-lowering slimming health products. METHODS： HPLC method was adopted. Using epigallocatechin gallate （EGCG） as a reference， relative correction factor （RCF） of EGCG to gallocatechin （EGC）， catechin （C）， epicatechin （EC）， gallocatechin gallate （GCG） and galloylepicatechin（ECG）were calculated. The contents of EGC， C， EC， GCG and ECG in 5 batches of samples were calculated through RCF. The contents of EGC， C， EC， GCG and ECG determined by external standard method were used as measured value. The similarity of the value determined by external standard method with the value calculated by quantitative analysis of multi-components via single marker method （QAMS） was evaluated with vector included angle cosine method. RESULTS： The linear ranges of EGCG，EGC，C，EC，GCG and ECG were 0.006 5-0.130 5 mg/mL（r＝0.999 8）、0.000 5-0.010 7 mg/mL（r＝0.999 7）、0.002 0- 0.040 0 mg/mL（r＝0.999 9）、0.015 3-0.305 3 mg/mL（r＝0.999 8）、0.000 8-0.015 5 mg/mL（r＝0.999 8）、0.004 0-0.079 2 mg/mL（r＝0.999 9）； RSDs of precision， stability and reproducibility tests were all lower than 2.0％.The recoveries were 95.07％-100.35％（RSD＝1.94％，n＝6）、95.24％-101.87％（RSD＝2.79％，n＝6）、96.08％-103.86％（RSD＝3.01％，n＝6）、97.51％-101.06％（RSD＝1.45％，n＝6）、96.01％-101.66％（RSD＝2.27％，n＝6）、96.20％-102.89％（RSD＝2.71％，n＝6）， respectively. There was no significant difference between measured value and calculated value. CONCLUSIONS： The method is simple， precise， stable and reproducible， and can be used for contents determination of catechins active components in lipid-lowering slimming health products.