OBJECTIVE： To provide policy recommendations for optimizing medicines distribution system reform in China. METHODS： Literature review and field investigation were used to mapping the medicines distribution system. Problems and influential factors were analyzed and policy recommendations for optimizing the medicines distribution system reform were put forward. RESULTS & CONCLUSIONS： Medicines distribution system has been undergoing a rapid development and transformation under the overall health system reform. Most medicines distributors are still with small scale， low concentration， high cost， low profitability， lack of core competence

development of new form facing challenges. A large number of drug distributors still follow the traditional business model， know little about modern drug supply chain management， and not understand their appropriate roles under the new social and economic development. Medical E-commerce face both opportunities and challenges in the process of developing. Drug distribution industry needs vertical and horizontal integration

speeds up the socialization of the third party logistics and the healthy development of the medical electricity supplier

improves and perfects the drug distribution supervision system which is suitable for the healthy development of new form.