OBJECTIVE： To develop a method for simultaneous determination of chlorogenic acid， geniposide， gentiopicroside， ferulic acid， baicalin and ammonium glycyrrhizinate in Yindan pinggan capsule. METHODS： HPLC method was adopted. The separation was performed on Wonda SilTM-C18 column with mobile phase consisting of acetonitrile-0.4％ phosphoric acid solution （gradient elution） at the flow rate of 0.8 mL/min. The detection wavelength were set at 325 nm （chlorogenic acid， ferulic acid）， 250 nm （geniposide， ammonium glycyrrhizinate） and 275 nm （gentiopicroside， baicalin）. The column temperature was  30 ℃. RESULTS： The linear ranges were 0.087-3.480 μg for chlorogenic acid （r＝0.999 8）， 0.201-8.040 μg  for geniposide （r＝0.999 7）， 0.200-8.000 μg  for gentiopicroside （r＝0.999 5）， 0.016-0.640 μg for ferulic acid （r＝0.999 9）， 0.105-4.200 μg for baicalin （r＝0.999 9） and 0.028-1.120 μg for ammonium glycyrrhizinate （r＝0.999 5）， respectively. The limits of quantitation were 1.31， 0.75， 1.14， 1.25， 0.94， 0.98 ng， and the limits of detection were 0.87， 0.67， 0.96， 0.93， 0.60， 0.88 ng， respectively. RSDs of precision， stability and reproducibility tests were lower than 2.0％； recoveries were 99.9％-101.9％ （RSD＝0.7％，n＝6）， 98.7％-100.9％（RSD＝0.9％，n＝6）， 98.1％-101.5％ （RSD＝1.4％，n＝6）， 98.5％-101.3％（RSD＝1.3％，n＝6）， 98.5％-101.7％ （RSD＝1.2％，n＝6）， 98.2％-101.4％（RSD＝1.2％，n＝6）， respectively. CONCLUSIONS： The method is simple and accurate ，can be used for simultaneous determination of chlorogenic acid， geniposide， gentiopicroside， ferulic acid， baicalin and ammonium glycyrrhizinate in Yindan pinggan capsule.