OBJECTIVE： To improve the work quality in Pharmacy intravenous admixture service （PIVAS）. METHODS： The major working links of PIVAS （labeling and drug admixture） were optimized， the work efficiency and error before and after optimization were compared. RESULTS： The work efficiency was improved and error was decreased by adding logo and adjusting work range of personnel when labeling and improving distribution principles of drugs to be allocated in horizontal laminar flow table when drug admixture； compared with before， the labeling time for each bag decreased from （2.69±0.17） s to （2.19±0.08） s， total time for admixture decreased from （104±2） min to （83±2） min， error rate of drug admixture decreased from 0.34％ to 0.16％. CONCLUSIONS： The optimized work flow had improved the work quality of PIVAS.