OBJECTIVE： To reflect the representative problems existing in the medication safety of public from the side， and provide reference for conducting the following public survey in a large area. METHODS： Questionnaires were used to investigate the knowledge of drug and medication habits of teachers in a senior high school in Beijing， and the received data was statistically analyzed. RESULTS： Totally 88 questionnaires were issued in this investigation， 84 effective questionnaires were acquired， with effective recovery of 95.45％. A few teachers had blind faith in intravenous infusion and preferred using antibiotics without doctor's diagnosis when they caught a cold and fever； 48.81％ of the respondents barely understood or only partly understood the drug instructions； 34.52％ didn't know that more serious adverse reactions induce by intravenous infusion were more serious than by oral treatment； 46.43％ rarely checked the period of validity of reserved drugs at home； 38.10％ didn’t following directions when taking drugs； 80.95％ had never received the education of medication safety， and 21.43％ of them had no intention to accept this education； when taking drugs for a long time， 79.76％ of them didn’t do regular examinations of blood routine， renal and liver function tests. CONCLUSIONS： The knowledge of drug use of the respondents in the school is poor， there are many misunderstandings existed in the medication habit， which prompts hidden trouble also exists in medication safety， and reflects hidden trouble commonly exists in medication safety for public from the side.