OBJECTIVE： To study the effect of canceling the maximum retail price limit on the accessibility of low-cost drugs in our hospital. METHODS： Based on the policies of canceling the maximum retail price， the low-cost drugs in the hospital management system were extracted to adjust the relevant data of price， compare the drug supply changes before and after the price adjustment and summarize the effect of canceling the maximum retail limit on the accessibility of low-cost drugs in our hospital. RESULTS： The price of 19 kinds of low-cost drugs in our hospital were adjusted， which were raised， for 1-4 times， the average daily cost increased to 0.06-2.51 yuan， with an increase proportion of 11％-309％. 16 varieties of order delivery rate increased， with increase proportion of 2％-100％， 1 variety decreased， with decrease proportion of 32％， 2 varieties showed the same distribution rate. CONCLUSIONS： Canceling the maximum retail price limit can promote the accessibility of low-cost drugs in our hospital.