OBJECTIVE： To investigate the cognition， evaluation and demands of medical staff to the clinical pharmacy work in the secondary and tertiary medical and health institutions in Xi’an city， and provide reference for further promoting the development of the local clinical pharmacy work. METHODS： 20 secondary and tertiary medical and health institutions in Xi’an city were randomly selected to conduct a random sampling questionnaire for physicians， nurses （senior nurses）， pharmacists （non-clinical pharmacist） and other medical technicians. And the results were statistically analyzed. RESULTS： Totally 1 020 questionnaires were sent out， 851 were effectively received with effective recovery of 83.4％. 45.9％ respondents knew clinical pharmacy， and “Colleague” was the main channel； 34.3％ thought clinical pharmacy “only maintained normal operation". 74.7％ surveyed medical staff， 92.6％ surveyed pharmacists and 70.6％ surveyed physicians thought clinical pharmacists “should” take round with the doctors and nurses； 44.3％ respondents showed “dissatisfaction” and “general satisfaction” with the clinical pharmacy work in their hospitals. 48.5％ respondents would take the initiative to consult the clinical pharmacist for medication； 45.5％ respondents partially accepted the drug information provided by clinical pharmacists. There were significant differences in the investigation results in aspects of respondents’ understanding level and channel for clinical pharmacy， cognition for development situation of clinical pharmacy， evaluation for clinical pharmacists participating round， demand for consulting the medication， acceptance for drug information provided by clinical pharmacists， and other items （P＜0.05）. CONCLUSIONS： The cognition and effect of clinical pharmacy work on medical staff need to be further strengthened， clinical pharmacists should also have solid clinical knowledge and the knowledge of medicine to meet the demand of medical staff in different positions， the acceptance of medical staff to the pharmaceutical care needs to be further improved. Clinical pharmacists should earnestly fulfill their job functions through various efforts to promote rational drug use.