OBJECTIVE： To study the differences for bidding price of anti-tumor drugs in centralized drug procurement， and to provide reference for further perfecting centralized drug procurement of province（region，city） in China. METHODS： The data of centralized drug procurement were collected from 25 provinces（region，city） in terms of general name of anti-tumor drugs， bidding manufacturers， bidding price， etc. Using mean， median， standard deviation， quartile range （QR） and coefficient of variation （CV） as index， the following aspects were compared and analyzed， including the situation of bidding anti-tumor drugs in each province（region，city）， the difference of chemicals price with Chinese patent medicines price， the difference of bidding price of same category in each province（region，city）， the difference of bidding price of same category in each manufacturers， the difference of bidding price of same category between imported drugs and domestic drugs， the difference of bidding price for Paclitaxel injection with same specification and dosage form from same manufacturers in each province（region，city）. RESULTS： In 25 provinces（region，city）， number of bidding anti-tumor drugs was 652， the average bidding price was （669.92±2 513.17） yuan， the median price was 104.35 yuan， QR＝254.28， CV＝3.75. The average bidding price of chemical anti-tumor drugs was 6.57 times as much as that of Chinese patent medicines. For 431 （66.10％） kinds of drugs， the distribution of difference between the highest bidding price and the lowest bidding price was within 1 times； CV of bidding price for 436 kinds （66.87％） was less than 0.2； pharmaceutical manufacturers of 14 drugs were more than 10， among which CV of 5 drugs was more than 0.5. CV of 63  imported drugs was equal to 2.10， and that of domestic drugs was equal to 1.90. The difference of bidding price for Paclitaxel injection from same manufacturer in different province（region，city） ranged 1.5-4.5 times from the higher to lower. CONCLUSIONS： The bidding price of same category is concentrated in each province（region，city）. The bidding price of same category from different manufacturers is dispersed. The imported drugs are more expensive than domestic drugs.