OBJECTIVE: To provide reference for the research, production and sales of Chinese patent medicines for the rheumatism and osteoporosis. METHODS: 200 consumers who used Chinese patent medicines for the rheumatism and osteoporosis from Guizhou Guiyang city, Zunyi city, Anshun city, Qiandongnan prefecture and Qiannan prefecture were stratified randomly sampled to develop the field questionnaire, and the data was statistically analyzed. RESULTS: Totally 200 questionnaires were sent out, 189 were effectively received with effective recovery of 94.5%. 54.0% of surveyed consumers’ diseases were rheumatism, 29.6% were osteoporosis, and 16.4% were both diseases; middle aged and elderly population accounted for 81.5%; when surveyed consumers selecting the pharmacies, the first consideration was whether the Medicare fixed (57.7%), followed by whether the drug price was appropriate (51.9%); the proportion of purchasing medicines based on the advertisement was low, only accounting for 13.2%; 67.7% of surveyed consumers paid much attention to the disease of rheumatism or osteoporosis, the proportion of consumers who used Chinese patent medicines for the rheumatism and osteoporosis by oral were 95.2% and 100%, respectively; skin itching, dizziness, nausea were the most common side effects; the proportion of surveyed consumers who believed that the efficacy and side effects were very important were higher, accounting for 82%, 48.2%, and other focused on the drug attributes followed by brand, taking convenience, price, etc., while consumers who used Chinese patent medicines for the rheumatism and osteoporosis preferred granules and tablets most; the consumers who need shopping guide and sometimes need accounted for 26.5% and 40.2%, respectively. CONCLUSIONS: The Chinese patent medicines for rheumatism and osteoporosis that taken orally have good market prospects, the elderly population is the main consumption, they pay more attention to the Medicare fixed, appropriate price, efficacy, side effects and easy to use, but less advertisement.