OBJECTIVE： To provide the new idea for clinical pharmacists providing pharmaceutical care in oncology department. METHODS： Applying the principles and methods of clinical pathway， the pharmaceutical care of anti-tumor drugs could be divided into before medication， during medication， after medication and patient education， according to the sequence of taking medicine. On the basis of evidence-based medicine， the care contents of each unit were established， and the pharmaceutical care pathway （PCP） was formed. During chemotherapy duration for a breast cancer metastasis patient with liver function injury， clinical pharmacists conducted pharmaceutical care for drug pretreatment， ADR monitoring and disposal， patient education， as well as put forward the proposal of drug treatment as supplementing calcium， adjusting the dose of epirubicin and paclitaxel targeting on PCP of zoledronic acid， epirubicin and paclitaxel. RESULTS： Physicians adopted the pharmacist’s recommendations. The patient suffered from joint and muscle pain during chemotherapy， and the symptom was relieved after symptomatic treatment by celecoxib； chest and back discomfort was relieved significantly after chemotherapy， and the disease condition kept stable. The patient was discharged from the hospital. CONCLUSIONS： PCP focus on the time， content and countermeasures of pharmaceutical care， the program and treatment results of pharmaceutical care， and promote standardization， formalization， simplification and procedure of pharmaceutical care. Clinical pharmacists conduct individualized pharmaceutical care rapidly targeting on PCP so as to deepen the communication of clinical pharmacists with physicians， nurses and patients， and promote the development of pharmaceutical care smoothly.