OBJECTIVE： To systematically review the efficacy of Buyi ganshen and Huoxue huayu prescriptions in the treatment of lumber disc hernition （LDH）， and provide evidence-based reference for clinic. METHODS： Retrieved from CNKI， Wanfang Databse， PubMed， Springer and Medline （from Jan. 2003 to Oct. 2015）， randomized controlled trials （RCT） and clinical controlled trials （CCT） about the Buyi ganshen and Huoxue huayu prescriptions （test group） versus other treatment （no Buyi ganshen and Huoxue huayu prescriptions，control group） in the treatment of LDH were collected. Meta-analysis was performed by using Rev Man 5.3 software after data extraction and quality evaluation by modified Jadad rating scale. RESULTS： Totally 39 studies were included， involving 3 921 patients. Results of Meta-analysis showed the total effective rate [OR＝4.41，95％CI（3.55，5.48），P＜0.001] in test group was significantly higher than control group， the score of visual analogue scale （VAS）[MD＝－1.05，95％CI（－1.49，－0.62），P＜0.001] and Oswestry disability index （ODI） score [MD＝－4.36，95％CI（－8.14，－0.58），P＝0.02] were significantly lower than control group， with statistical significances. There was no significant difference in the Japanese Orthopaedic Association assessment treatment （JOA） score [MD＝1.48，95％CI（－1.41，4.37），P＝0.32] in 2 groups. CONCLUSIONS： Buyi ganshen and Huoxue huayu prescriptions show good efficacy in the treatment of LDH， which can obviously improve the low back pain， numbness of the lower limbs， radition pain and other symptoms of discomfort.