OBJECTIVE： To explore the effect of health intervention on blood pressure， medication compliance and the quality of life in elderly patients with hypertension. METHODS： 64 elderly patients with hypertension were selected and randomly divided into observation group and control group， with 32 cases in each group. Both groups were given Amlodipine besylate tablet 5 mg， qd. Control group received routine hypertension knowledge education and regular recheck by guidance. Observation group additionally received health intervention on the basis of control group. The blood pressure control， cognitive level of patients to hypertension， medication compliance， the level of trust in physicians and quality score of life were compared between 2 groups before and after intervention. RESULTS： There was no statistical significance in systolic blood pressure and diastolic blood pressure between 2 groups before intervention （P＞0.05）. After intervention， systolic blood pressure and diastolic blood pressure of 2 groups were decreased significantly， and the observation group was significantly lower than the control group， with statistical significance （P＜0.05）. There was no statistical significance in cognitive level of patients to hypertension， medication compliance， the level of trust in physicians and quality score of life between 2 groups before intervention （P＞0.05）. After intervention， the observation group was better than the control group in terms of cognitive level of patients to hypertension， medication compliance， the level of trust in physicians and quality score of life， with statistical significance （P＜0.05）. CONCLUSIONS： Health intervention can effectively improve the cognitive level of elderly patients with hypertension to hypertension， improve the medication compliance and the level of trust in physicians， control blood pressure and improve the quality of life.