OBJECTIVE： To study the chemical constituents of the flower of Zang Epipremnum aureum. METHODS： The constituents of ethyl acetate extract of the flower of E. aureum were separated and purified with varied chromatographic techniques， and the structures were identified based on spectral data and chemical properties. RESULTS： Ten compounds were isolated from ethyl acetate extract of the flower of E. aureum， they were identified as rutamontine （1）， edgeworoside C （2）， edgeworin （3）， tiliroside （4）， helichrysoside （5）， kaempferol （6）， 2，4-dihydroxypheny-2-hydroxy-4-metho-xybenzyl-ketone （7）， ethyl caffeate （8）， phthalic acid bis-（2-ethyl-hexyl） ester （9） and noreugenin （10）. CONCLUSIONS： Compound 7 is firstly isolated from natural source， compounds 5， 8 and 9 is firstly isolated from the family Thymelaeaceae， compound 6 is firstly isolated from Edgeworthia and compound 2 and 10 are firstly isolated from the flowers of E. aureum. The study lays certain foundation for the quality evaluation of E. aureum.