OBJECTIVE： To effectively improve the efficiency of experimental teaching， and provide reference for improving the training level of the oversea pharmacy talents. METHODS： By reforming the teaching guideline and teaching contents （including the content， teaching language， assessment， assisted means， as well as comprehensive and self-designed experiments of innovation）， the reform and exploration of teaching mode of pharmaceutical experiments for overseas students in Ji’nan University were concluded. RESULTS： The training target of “application-oriented pharmacy talents” was presented for the oversea pharmacy talents. The contents were reformed by satisfying professional needs， international standards and strengthening pertinence with Chinese and English teaching to establish comprehensive index testing system， the teaching mode was reformed and explored by applying multi-media， software and network and strengthening the independent innovation with integrated and designing experiment. CONCLUSIONS： The experimental teaching has broken the inherent experimental teaching model and framework for the oversea pharmacy talents and improved their learning interest and effect， which laid the foundation for cultivating them to be the application-oriented pharmacy talents.