OBJECTIVE： To observe the clinical efficacy and safety of Shuxuetong combined with acupuncture in the treatment of patients with stroke during recovery period. METHODS： 80 patients with stroke during recovery period were selected and divided into observation group and control group， with 40 cases in each group according to random number table method. Control group received acupuncture， 6 times a week. Observation group was additionally given Shuxuetong injection 6 ml added into 0.9％ Sodium chloride injection 250 ml， ivgtt， qd， for one month. Clinical efficacy of 2 groups were observed as well as intracranial [arteriae cerebri anterior （ACA）， middle cerebral artery （MCA）， basilar artery （BA）] blood flow rate， neurological deficit score （NIHSS）， cognitive ability （MMSE） score， Fugl-Meyer activity score and Fugl-Meyer balance score before and after treatment. The occurrence of ADR was compared. RESULTS： Total effective rate of observation group was 95.0％， which was significantly higher than that of control group （70.0％）， with statistical significance （P＜0.05）. Compared with before treatment， blood flow rate of ACA and MCA were increased significantly in observation group after treatment， and were higher than those of control group with statistical significance （P＜0.05）. NIHSS， MMSE， Fugl-Meyer activity score and Fugl-Meyer balance score of 2 groups improved significantly after treatment， the observation group was better than the control group， with statistical significance （P＜0.05）. No obvious ADR was found in 2 groups. CONCLUSIONS： Shuxuetong combined with acupuncture show significant therapeutic efficacy， and improve intracranial blood flow rate and neurologic function with good safety.