OBJECTIVE： To provide reference for improving the service quality of outpatient pharmacy in hospital. METHODS： A questionnaire survey was conducted to investigate and analyze the patients’ satisfaction and related influential factors to outpatient pharmacy in a third grade class-A hospital in Chengdu. RESULTS： Totally 165 questionnaires were sent out， and 150 were effectively received with effective recovery of 90.91％. The total score for patients’ satisfaction was （44.67±7.81） scores， and the rate of satisfaction was （81.22±14.19）％. The top three entries were “the will you choose to come to our hospital again if necessary”， “the notices about time and place for taking the medicine” and “the overall evaluation of the professional ethics of medical staff”， scored 4.38， 4.25 and 4.25， respectively； the last three entries were “waiting time for taking medicine”， “the notices about how long it takes to take the medicine” and “service facilities and environmental facilities for drug taking”， scored 3.55， 3.63 and 3.95， respectively. The top three suggestions were “long waiting time for taking medicine and inconvenient”， “noisy environment， bad order” and “expensive drugs charges but less reimburse”. The univariate analysis and multivariate analysis showed that gender， age， marital status， education， occupation， family income per month， resident， drug taking times and payment etc. factors showed no significant effects on patients’ satisfaction scores （P＞0.05）. CONCLUSIONS： The degree of patients’ satisfaction in outpatient pharmacy have no obvious specificity and preference， the key to improve the degree of satisfaction lies on strengthening the service of the hospital and the perception of the patients. While the next research will focus on how to find the breakthrough points and key points to improve the experience of waiting， standardize process management and logistics management， and make patients aware of the service development.