OBJECTIVE： To provide reference for the rational use of TCM injections. METHODS： 487 medical records using TCM injection in our hospital from Jul. to Dec. 2014 were selected as control group， another 500 from Jan. to Jun. 2015 were intervention group. Utilization， rationality and adverse reactions of TCM injection between 2 groups were compared. RESULTS： According to the intervention by clinical pharmacists， the sales amount and utilization rate of top 10 TCM injection in our hospital were lower significantly. The irrational utilization rate of 5 types （totally 26 varieties） in intervention group decreased （21.60％ vs. 43.33％）， incidences of adverse reactions reduced （3.00％ vs. 7.39％）， compared with control group， the differences were statistically significant （P＜0.05）. Treatment cost per capita [（217.17±22.64） yuan vs. （480.77±21.35） yuan] and hospitalization time [（6.50±1.99）d vs. （10.02±3.25）d] in intervention group were significantly lower or shorter than control group， the differences were statistically significant （P＜0.05）. CONCLUSIONS： Implementing pharmaceutical interventions can strengthen the sense of clinicians’ rational use of TCM injection， raise the level of rational use of drugs and reduce adverse reactions and medical errors.