OBJECTIVE： To provide reference for the rational drug use of traditional TCM injection. METHODS： Medical records of 792 patients receiving TCM injection were collected from Qingdao Municipal Hospital in the first quarter of 2014 （before intervention） and 836 patients collected from the first quarter of 2015 （after intervention）， and then analyzed comparatively in respects of patient’s gender information， rationality of TCM injection， irrational drug use， ADR. RESULTS： After intervention， the use of TCM injection in the hospital became standard gradually， and rational rate increased from 42.42％ to 69.98％. Irrational drug use as super-indication medication， overdose， inadequate solvent amount decreased； the ratio of TCM injection prescription cost per capita decreased from 16.64％ to 12.59％； the incidence of ADR decreased from 6.94％ to 2.51％， with statistical significance （P＜0.05）. Except that the amount of Andrographolide for injection， Xuesaitong for injection， Zhengqing fengtongning injection， Reduning injection increased， those of other TCM injection decreased. CONCLUSIONS： Pharmaceutical intervention measures of clinical pharmacists are effective and feasible， and promote rational and standard use of TCM injection.