OBJECTIVE： To provide reference for the development of online drugstores in China based on mobile port. METHODS： The development of online drugstores in China based on mobile port was analyzed by SWOT （strengths， weaknesses， opportunities， threats） analysis to put forward suggestions. RESULTS & CONCLUSIONS： Online drugstores based mobile port included vertical management in which pharmaceutical E-commerce manager directly participate， non-vertical management which mainly provide information inquiry and price comparison. It has advantage in breaking through time and space obstacle， optimizing information display， integrating consumer’s information accurately， improving human efficiency， etc. They are weak in timeliness， business scope and sale function， the quality of pharmaceutical care， user activity， etc. They have the opportunities as annual increase of mobile E-commerce market scale and huge market development potential； they also face various threats， such as the inconformity between main users of mobile port and main purchasers， consumer low-trust， health-care polity barrier breakthrough failure， the lack of legal regulations for medical and pharmaceutical software， etc. It is suggested that companies operate further accurately and the government speed up the formulation and implementation of laws and regulations.