OBJECTIVE： To investigate the characteristics and general regularity of ADR induced by Danhong injection， and to provide reference for rational drug use in the clinic. METHODS： Using “Danhong injection” and “ADR”as keywords， retrieved from CJFD， literatures published during 2005-2015 were collected and analyzed statistically in repsects of patient’s gender and age， disease and allergic history， drug combination， occurrence time of ADR and clinical manifestations， etc. ?RESULTS： A total of 24 literatures were collected， involving 360 cases. Female patients were more than male （66.11％ vs. 33.89％）； ADR often occurred within 30 min during medication （169 cases， 46.94％）； main clinical manifestations were lesion of skin and its appendents （163 cases， 42.89％）， ?systemic injury （72 cases， 18.95％）. The severe one would suffer form allergic shock. ?CONCLUSIONS： Great importance should be attached to the indication of Danhong injection， treatment based on syndrome differentiation， rational drug use and close monitoring. Constant vigilance is necessary to the occurrence of ADR.