OBJECTIVE： To establish a method for the determination of 1，1-ethanediol diacetate and acetic acid in flurbiprofen axetil. METHODS： Capillary gas chromatography was performed on the column of DB-FFAP capillary column by temperature programmed， the inlet temperature was 150 ℃， flame ionization detector was chosen， detector temperature was 290 ℃， carrier gas was nitrogen at a flow rate of 1.0 ml/min， injection volume was 1.0 μl， and split ratio was 5 ∶ 1. RESULTS： 1，1-ethanediol diacetate and acetic acid were well-separated； and the linear ranges was 0.78-19.55 g/ml （r＝0.999 7） and 7.69-64.11 μg/ml （r＝0.999 3）， respectively； the limits of quantification were 0.78 μg/ml and 7.69 μg/ml， and limits of detection were 0.23 μg/ml and 2.56 μg/ml for 1，1-ethanediol diacetate and acetic acid respectively； RSDs of precision and reprocudibility tests were lower than 3％， and stability test was lower than 5％； recoveries were 97.6％-100.4％（RSD＝0.94％，n＝9） and 93.6％-100.4％（RSD＝0.94％，n＝9）； and the test results for 3 batches of flurbiprofen axetil were met the specification. CONCLUSIONS： The method is simple， accurate and reliable， and can be used for the determination of 1，1-ethanediol diacetate and acetic acid in flurbiprofen axetil.