OBJECTIVE： To know the utilizatior of Shenfu injection （SFI） in our hospital， and provide reference for rational use of SFI. METHODS： In respective study， patients received SFI from the Hospital Information System （HIS） in surgery department in our hospital from Jan. 2013 to Dec. 2014 were analyzed statistically in aspects of general situation， indications， usage and dosage， course of treatment， drug combination， etc. And the incidence of ADR/ADE was monitored. RESULTS： The 1 247 surgery inpatients used SFI distributed in thyroid and galactophore department （634 cases）， comprehensive minimally invasive department （292 cases）， gastrointestinal surgery department （250 cases）， urology department （64 cases） and cardiothoracic surgery department （7 cases）， including 466 male and 781 female， the ratio of male to female was 1 ∶ 1.68， average age was 58.50 years； it mainly used in perioperative medication （78.11％） and treated for tumors （11.23％）， treatment course concentrated on 2-7 d （71.45％）， dosage mainly was 100 ml （70.01％）； combination medication were mainly pantoprazole sodium， Fructus bruceae injection， Xueshuantong for injection （lyophilized）， etc. The nonstandard phenomenon was existed in indications， dosage， solvent selection， medication frequency， drug combination， etc. There were no obvious ADR/ADE related to SFI. CONCLUSIONS： More attention must be paid to the irrational use of SFI in surgery clinic of our hospital， the safety of traditional Chinese medicine injection in clinical use should be correctly understood， achieve dialectical therapy and rational drug use.