OBJECTIVE： To observe clinical efficacy and safety of Jiajian shenghua decoction combined with antibiotics in the treatment of blood-stasis type postpartum fever. METHODS： 178 patients with blood-stasis type postpartum fever were randomized into observation group and control group， with 89 cases in each group. Control group received basic treatment as physical cooling， fluid infusion， and adopt suitable antibiotics according to the results of bacterial culture test； observation group was additionally given Jiajian shenghua decoction， one dose a day， decocting 300 ml with water， day and night at twice. Treatment course of 2 groups lasted for 5 d. Clinical efficacy was compared between 2 groups， and white blood cell count， case number of body temperature returned to normal and lab indexes were observed before and after treatment. The occurrence of ADR was also observed. RESULTS： The overall response rate （94.38％） of observation group was significantly higher that （82.02％） of control group， with statistical significance （P＜0.05）； 1 d， 3 d， 5 d after treatment， white blood cell count of 2 groups decreased significantly compared to before treatment， the observation group was more significant than control group， with statistical significance （P＜0.05）； there was statistical significance in the case number of body temperature returned to normal between 2 groups 1 d， 3 d， 5 d after treatment， with statistical significance （P＜0.05）； the observation group was more than control group， with statistical significance （P＜0.05）. The plasma viscosity， erythrocyte sedimentation rate， fibrinogen of 2 groups decreased significantly after treatment， compared to before treatment， and the observation group was significantly lower than control group， with statistical significance （P＜0.05）. No obvious ADR was found in 2 groups during treatment. CONCLUSIONS： Jiajian Shenghua decoction can increase the effect and has good safety for blood-stasis type postpartum fever.