OBJECTIVE：To provide reference for development of hospital pharmacy and clinical pharmacy in south Sichuan. METHODS： Questionnaire was used to investigate the general situation of secondary and tertiary hospitals in 4 cities of south Sichuan in aspects of partition layout， staffing situation and job content. The results were statistically analyzed. RESULTS：A total of 40 questionnaires was sent out， 35 were effectively received with the effective rate of 87.50％. The partition layout was unreasonable in most surveyed hospitals， and the rate of reaching the standard about the area of drug dispensing sector and warehouse was below 85％. There were 1 042 pharmacists in 35 hospitals， which were mainly female of younger than 45 years old. In secondary and tertiary hospitals， the rate of pharmaceutical professional and technical personnel of health technology， full-time undergraduate and vice-high above title accounted for 4.78％ and 3.67％， 17.37％ and 31.27％， 3.15％ and 10.73％， respectively. The number of full-time clinical pharmacists was 24 and 69 in secondary or tertiary hospitals， mainly primary title， middle title and undergraduate， of whom 26 （27.96％） passed job training of National Health and Family Planning Commission， 4 （4.30％） passed teaching qualifications training. The rate of pharmacists mainly engaged in drug dispensing and clinical pharmacy was 6.32％ and 11.03％ in secondary and tertiary hospitals， respectively. CONCLUSIONS： The research shows irrationality of partition layout， the shortage of highly educated and highly titles personnel， especially the clinical pharmacy professionals. The large differences exist in hospitals of different levels in several aspects， and the main body of hospital pharmacy should turn to clinical pharmacy.