OBJECTIVE： To optimize the extraction technology of total lignans from pine needles of Cedrus deodara. METHODS： Using ethanol volume fraction， ratio of liquid to solid and extraction time as response factor， the content of total lignans as response value， the response surface methodology test was conducted based on Box-Behnken design to optimize the extraction technology of total lignans from pine needles of C. deodara. RESULTS： The optimal extraction technology was as follows as ethanol volume fraction of 78％， ratio of liquid to solid 25 ∶ 1， extraction time 1.75 h. The content of total lignans from pine needles of C. deodara was 99.2 mg/g， which was close to predicted value 100.49 mg/g， with relative deviation of 0.65％. CONCLUSIONS： Optimized extraction technology of pine needles of C. deodara by response surface methodology is feasible and stable， and has good predictability.