OBJECTIVE： To investigate rules and characteristics of ADR induced by antigout agents， and to provide reference for clinical rational drug use. METHODS： A total of 146 literatures， 167 putients of ADR induced by antigout agents， which were reported during Jan. 1979－Dec. 2014. RESULTS： Of 167 ADR cases， the ratio of male to female was 5.4 ∶ 1， and ADR patients aged above 70 years occupied the highest proportion （34.14％）； Most ADR were induced by allopurinol（137 cases） ADR induced by antigout agents mainly were dermal system injury （60.00％）， systemic reaction （9.19％）， urinary system injury （5.95％）， etc. and the specific performance manifested as erythra （51 cases）， dermatitis exfoliativa （38 cases）， drug hypersensitivity syndrome （13 cases）， bullous epidermal necrolysis type of drug eruption （11 cases）， Stevens-Johnson syndrome （9 cases） and so on. New and severe ADR were 66 cases， 13 cases of severe ADR were dead. CONCLUSIONS： ADR induced by antigout agents is common in clinical and should be treated promptly， patient’s care also should be strengthen to ensure patient medication safety and improve clinical treatment.