OBJECTIVE： To provide reference for perfecting retail pharmacies supervision and pharmaceutical care mode in China. METHODS： Using“drug store”“retail pharmacy”“community pharmacy”“pharmaceutical care” as keywords， the literatures about pharmacy management and pharmaceutical care during 2005-2014 were retrieved from CNKI， Medline， ISI Web of Knowledge， Scopus and other database. The experience and method of pharmacies management and pharmaceutical care in some countries and regions were summarized in respects of the development of retail pharmacies， operation mode and management system， etc. RESULTS： There were 256 literatures in total， including 234 domestic literatures and 22 foreign literatures. More than half of retail pharmacies were chain pharmacies in some foreign countries and regions， and there were specific requirements and clear compensation mechanism for pharmaceutical care； owner’s identity， position， quantity， population distribution， staff composition and other aspects were checked strictly. The chain pharmacies accounted for less than 20％ of total pharmacies in China. However， the pharmaceutical care was still in early stages in China， which resulted from the serious shortage of licensed pharmacists and incomplete relevant laws or regulations； there was no clear requirement for the number of population served by one pharmacy and geographic distribution in China； they all showed poor operability in most cases. CONCLUSIONS： Learning from the pharmacy management and pharmaceutical care models of Europe and the United States and other developed countries and regions， government should take measures to improve the chain operation level of pharmacies and should clear the set-up requirements and the regional distribution of pharmacies. What’s more， government should control retail drug market appropriately， improve the regulation of the drug market and control the quality of the drugs in the process of drug production， circulation and sale； perfect prosecution mechanism of prescription drug sale violation， and increase penalties； improve the quality of pharmaceutical care through completing the relevant laws and regulations of pharmaceutical care and licensed pharmacists.