OBJECTIVE： To provide reference for standardizing chemotherapy drug use in tumor patients， and to investigate the points of pharmaceutical care. METHODS： 2 242 medical records of tumor chemotherapy were sampled from 4 third grade class A hospitals to investigate chemotherapy drug plan and pharmaceutical care. The reasons for irrational drug use were analyzed， and the points of pharmaceutical care were summarized. RESULTS： There were 1 295 cases of irrational chemotherapy drug use， among which irrational dose accounted for 26.87％； irrational antiemetic drugs use 14.44％； irrational chemotherapy plan 13.13％； irrational drug selection 10.89％； irrational dosing order 10.04％. 6 items of rational chemotherapy drug use monitoring index were summarized， which were rationality of scheme selection， drug selection， drug dose， dosing time and order， solvent concentration， route of administration， adjuvant drug use； covering the process of chemotherapy. CONCLUSIONS： Pharmaceutical care can be standardized through rationality investigation on chemotherapy drug use of tumor patients， which contributes to improving pharmaceutical care level of clinical pharmacists， and rational drug use the clinic.