OBJECTIVE：To optimize the comprehensive extraction technology of crude polysaccharide and total saponins from Fuling kugua capsule. METHODS：Based on single factor test，using liquid ratio，extraction time and extraction times as response factors，the parameters of extraction technology of crude polysaccharides and total saponins from Fuling kugua capsule were optimized by using Box-Behnken design of response-surface method. RESULTS：The optimal extraction technology was as follows as liquid ratio of 1 ∶12，extraction time for 1.4 h，extraction times for 2 times. Under this technology，the yield of crude polysaccharide was 14.44％（RSD＝0.14％，n＝3），and that of total saponins was 1.33％（RSD＝0.75％，n＝3）. They were close to predicted value 14.69％ and 1.36％，and the deviation were 1.70％ and 2.21％. CONCLUSIONS：Measured value is close to predicted value，which indicates comprehensive extraction parameters optimized by response-surface methodology can be sued for the extraction of crude polysaccharide and total saponins from Fuling kugua capsule.