OBJECTIVE： To systematically evaluate the efficacy and safety of Astragali radix injection combined with trimetazidine in the treatment of viral myocarditis （VMC）， and provide evidence-based reference for clinical treatment. METHODS： Retrieved from PubMed， CBM， CJFD， VIP and Wanfang Database， randomized controlled trials（RCT） about Astragali radix injection combined with trimetazidine（test group） vs. western conventional treatment and（or） trimetazidine alone （control group） in the treatment of VMC were collected. After quanlity evaluation and data extraction， Meta-analysis was conducted by using Rev Man 5.2 statistics software. RESULTS：A total of 14 RCT were included， involving 1 324 patients. Results of Meta-analysis showed the total effective rate[RR＝1.32，95％CI（1.25，1.39），P＜0.001]， lactate dehydrogenase level [MD＝－99.80，95％CI（－135.52，－64.08），P＜0.001] and creatine kinase level [MD＝－49.66，95％CI（－80.43，－18.90），P＝0.002] in test group were significantly lower than those of control group， there was sgnificant difference between 2 groups； and there was no significant difference in the incidence of adverse reactions[RR＝0.86， 95％CI（0.48，1.55），P＝0.61]. CONCLUSIONS： Astragali radix injection combined with trimetazidine has good efficacy and safety in the treatment of VMC.