OBJECTIVE：To establish a method for the simultaneous determination of baicalin， baicalein and wogonin in Huatan pingchuan tablet. METHODS： HPLC was performed on the column was Diamonsil C18 with mobile phase of methanol -0.1％ phosphoric acid（gradient elution） at a flow rate of 1.0 ml/min， detection wavelength was 277 nm， column temperature was 30 ℃，and the injection volume was 10 μl. RESULTS：The linear range was 0.069 04-0.690 4 μg for baicalin（r＝0.999 4），0.054 56- 0.5456 μg for baicalein（r＝0.999 6） and 0.030 36-0.303 6 μg for wogonin（r＝0.999 1）； RSDs of precision， stability and reproducibility tests were lower than 2％； recoveries were 97.64％-99.06％（RSD＝0.57％，n＝6）， 98.31％-100.64％（RSD＝0.85％，n＝6） and 97.53％-99.48％（RSD＝0.76％，n＝6）. CONCLUSIONS： The method is simple， stable and reproducible， and can be used for the contents determination of baicalin， baicalein and wogonin in Huatan pingchuan tablet.