OBJECTIVE： To investigate the prognosis of coronary heart disease complicated with heart failure patients abandoning percutaneous coronary intervention （PCI） and receiving drug comprehensive therapy. METHODS： From Dec. 2010 to Jul. 2012， 217 patients with coronary heart disease complicated with heart failure in our hospital were divided into operation group （105 cases） and non-operation group （112 cases）. Based on routine treatment， operation group was given aspirin combined with clopidogrel before and after PCI， and non-operation group was given aspirin combined with clopidogrel all the time. The patients were followed up regularly during discharging from hospital to May 2015 by outpatient， telephone and coronary angiography rechecking， lasting for 24-38 months. Death cases， readmission and revascularization again caused by main adverse cardio-cerebrovascular events were recorded during follow-up period. RESULTS： 7 cases and 8 cases in operation group and non-operation group did not accept follow-up； median follow-up time was 33 months and 32 months， respectively. Case number of myocardial infarction， heart failure and death in non-operation group was more than operation group， with statistical significance （P＜0.05）. 94 patients survived in operation group in 3 years， with survival rate of 95.9％； 66 in non-operation group， with survival rate of 63.5％； with statistical significance （P＜0.05）. The survival time of non-operation group was shorter than that of operation group， with statistical significance （P＜0.05）. CONCLUSIONS： Although we still cannot get the conclusion that PCI is a better treatment or drug therapy is better. But the survival rate of patients are not optimistic 3 years after abandoning PCI coronary heart disease patients with severe myocardial ischemia should choose PCI firstly.