OBJECTIVE：To explore medical course construction for community pharmaceutical service talents cultivation. METHODS： According to the requirements for community pharmaceutical service talents cultivation in vocational colleges， Yancheng Health Vocational & Technical College strengthened the medical course construction by optimizing the curriculum system structure， selecting the teaching contents， reinforcing the students’ vocational ability education and infiltrating humanistic education. RESULTS： In terms of medical curriculum structure， the college integrated the basic medical and clinical disciplines respectively into Essentials of Basic Medicine and Essentials of Clinical Medicine. In terms of selection the teaching contents， the college tried to weaken medical discipline consciousness and to follow the logical relationship among medical disciplines， not only pursuing the integrity and systematization of the knowledge from different subjects. Besides， the college added teaching contents， strengthened the cultivation of vocational skills， and increased the practical teaching contents as well as infiltrates the humanistic education into the practical teaching. CONCLUSIONS： Strengthening medical course construction makes it better for medical course structure and teaching contents to achieve the requirements of the pharmaceutical service talent cultivation goals of “good command of medicine and pharmacy”.