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1.漳州卫生职业学院药学系,福建 漳州 363000
2.福建省漳州市医院药学部,福建 漳州 363000
3.漳州市聚善堂药业有限公司,福建 漳州 363000
Published:15 January 2023,
Received:02 May 2022,
Revised:01 December 2022,
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高伟城,王小平,肖晓琳等.基于熵权TOPSIS法综合评价不同产地枇杷叶质量 Δ[J].中国药房,2023,34(01):72-77.
GAO Weicheng,WANG Xiaoping,XIAO Xiaolin,et al.Comprehensive evaluation of the quality of Eriobotrya japonica leaves from different producing areas based on entropy weight TOPSIS method[J].ZHONGGUO YAOFANG,2023,34(01):72-77.
高伟城,王小平,肖晓琳等.基于熵权TOPSIS法综合评价不同产地枇杷叶质量 Δ[J].中国药房,2023,34(01):72-77. DOI: 10.6039/j.issn.1001-0408.2023.01.14.
GAO Weicheng,WANG Xiaoping,XIAO Xiaolin,et al.Comprehensive evaluation of the quality of Eriobotrya japonica leaves from different producing areas based on entropy weight TOPSIS method[J].ZHONGGUO YAOFANG,2023,34(01):72-77. DOI: 10.6039/j.issn.1001-0408.2023.01.14.
目的
2
对不同产地枇杷叶的质量进行综合评价。
方法
2
以不同产地的30份枇杷叶为样品,采用热浸法测定其醇溶性浸出物含量,采用紫外分光光度法分别测定其总黄酮含量和总三萜酸含量,采用高效液相色谱法测定其5个三萜酸类成分(野鸦椿酸、山楂酸、科罗索酸、齐墩果酸及熊果酸)的含量。采用熵权逼近理想排序法(TOPSIS)综合评价不同产地枇杷叶的质量;运用SPSS 22.0软件对枇杷叶片重、综合评价值、醇溶性浸出物含量、总黄酮含量、总三萜酸含量及5个三萜酸类成分含量进行双变量相关性分析。
结果
2
30份不同产地枇杷叶中醇溶性浸出物含量为(24.56±0.08)%~(34.85±0.13)%,总黄酮含量为(4.69±0.11)~(14.23±0.27) mg/g,总三萜酸含量为(27.58±0.59)~(63.95±1.27) mg/g,野鸦椿酸、山楂酸、科罗索酸、齐墩果酸、熊果酸的含量分别为(0.728±0.011)~(6.064±0.063)、(0.526±0.013)~(3.245±0.022)、(1.222±0.025)~(8.807±0.094)、(0.856±0.021)~(2.931±0.075)、(4.704±0.087)~(11.806±0.283) mg/g;熵权TOPSIS法分析结果显示,综合评价值排名前3位的样品依次为S14(福建漳州云霄县火田镇产)、S19(广西钦州钦南区产)及S29(安徽亳州涡阳县产)。枇杷叶的综合评价值与野鸦椿酸、山楂酸、科罗索酸、齐墩果酸和熊果酸这5个三萜酸类成分的含量均呈正相关(
P
<0.01),且枇杷叶片重与综合评价值呈正相关(
P
<0.01)。
结论
2
不同产地枇杷叶质量存在较大差异,其中以福建漳州云霄县火田镇产、广西钦州钦南区产和安徽亳州涡阳县产枇杷叶的质量相对较优;枇杷叶片重与其品质呈正相关。
OBJECTIVE
2
To comprehensively evaluate the quality of
Eriobotrya japonica
leaves from different producing areas.
METHODS
2
The contents of alcohol-soluble extracts were determined by hot-dipping method using 30 batches of
E. japonica
leaves from different producing areas as samples. The contents of total flavonoids and total triterpene acids were determined by ultraviolet spectrophotometry. The contents of five kinds of triterpenic acids (euscaphic acid,crataegolic acid,corosolic acid,oleanolic acid and ursolic acid) were determined by HPLC. The quality of
E. japonica
leaves from different producing areas was comprehensively evaluated by using entropy weight technique for order preference by similarity to an ideal solution (TOPSIS). The bivariate correlation analysis of
E. japonica
leaves was conducted by SPSS 22.0 software in terms of weight, comprehensive evaluation value, the content of alcohol-soluble extract, the contents of total flavonoids, total triterpene acids and five triterpenic acids.
RESULTS
2
The contents of alcohol-soluble extract in 30 batches of
E. japonica
leaves were (24.56±0.08)%-(34.85±0.13)%; the contents of total flavonoids were (4.69±0.11)-(14.23±0.27) mg/g; the contents of total triterpene acid were (27.58±0.59)-(63.95±1.27) mg/g; the contents of euscaphic acid, crataegolic acid, corosolic acid, oleanolic acid and ursolic acid were (0.728±0.011)-(6.064±0.063), (0.526±0.013)-(3.245±0.022), (1.222±0.025)-(8.807±0.094), (0.856±0.021)-(2.931±0.075), (4.704±0.087)-(11.806±0.283) mg/g, respectively. The analysis result of entropy weight TOPSIS method showed that the top three samples with comprehensive evaluation values were S14 (Huotian Town, Yunxiao County, Zhangzhou, Fujian), S19 (Qinnan District, Qinzhou, Guangxi) and S29 (Guoyang County, Bozhou, Anhui). Comprehensive evaluation of
E. japonica
leaves was positively correlated with the contents of five kinds of triterpenic acids, such as euscaphic acid, crataegolic acid, corosolic acid, oleanolic acid and ursolic acid (
P
<0.01). The weight of
E. japonica
leaves was positively correlated with the comprehensive evaluation value (
P
<0.01).
CONCLUSIONS
2
The qualities of
E. japonica
leaves from different producing areas are very different. Among them, the qualities of
E. japonica
leaves from Huotian Town, Yunxiao County, Zhangzhou of Fujian, Qinzhou Qinnan District of Guangxi, and Bozhou Guoyang County of Anhui are relatively better. The weight of
E. japonica
leaves is positively correlated with their quality.
枇杷叶三萜酸类成分总黄酮熵权逼近理想排序法相关性分析产地
triterpene acidstotal flavonoidsentropy weight TOPSIS methodcorrelation analysisproducing areas
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