ZHANG Xiaoxia,LIU Ruixin,WANG Yaxu,et al.Processing evolution and modern research progress of Artemisia argyi[J].ZHONGGUO YAOFANG,2023,34(06):758-762. DOI: 10.6039/j.issn.1001-0408.2023.06.22.
Processing evolution and modern research progress of Artemisia argyi
Lévl. et Vant.的干燥叶,是我国常用传统中药。笔者通过查阅传统医药古籍、现代标准规范及文献资料,利用Cytoscape软件对艾叶炮制及炮制品功效的历史沿革进行梳理和可视化呈现。艾叶炮制最早可追溯至汉代,鼎盛于宋代和明代;古代炮制方法较多,包括净制、切制、炒制、辅料制(醋、酒、盐、制炭、米泔水、硫磺、药汁、枣泥制)和其他制法(焙制、绞汁、制绒);现代常用炮制方法包括净制、醋制、制炭和制绒等,与古代炮制方法相比较为单一;生熟艾叶功效及应用差异明显,虽艾叶古今炮制作用皆以减少毒副作用和增强温经止血等功效为主,但现代药理研究仅见净艾叶、醋艾叶和醋艾炭,其他炮制品未见延承研究,炮制机制尚不明确。建议在后续探索研究时,研究者可结合药用植物艾的本草特征和中药饮片艾叶的炮制特色,建立多维度炮制标准研究体系,以系统探索艾叶炮制前后的转化规律,清晰阐述其炮制的科学内涵。
Abstract
Artemisia argyi
is the leaves of compositae plants of
A. argyi
Lévl. et Vant., which is a traditional Chinese medicine commonly used in China. The analysis was carried out by consulting traditional medical classics, modern standard norms and literature, and using Cytoscape software to sort out and visualize the evolution of the
processing and the efficacy of processed products. The processing of
A. argyi
was first made in the Han dynasty and was popular in the Song and Ming dynasties. There were many processing methods in ancient times, including net processing, cutting, frying, processing with auxiliary material (vinegar, wine, salt, charcoal, rice water, sulfur, medicinal juice, jujube mud processing) and other processing methods (baking, winching, making herbs into wool). Modern common processing methods included purification, vinegar processing, charcoal processing and making herbs into wool, which are relatively simple compared with ancient processing methods. There were obvious differences in the efficacy and application of raw and processed products of
A. argyi
. Although the processing effects of
A. argyi
in ancient and modern times were mainly to reduce toxic side effects and enhance the effects of warming meridians and hemostasis, only the purified
A. argyi
, vinegar-processed
A. argyi
and vinegar-processed
A. argyi
charcoal could be seen in the present studies, other processed products had not been inherited and studied, and the processing mechanism was still unclear. It is suggested that in the later exploration and research, researchers can establish a multi-dimensional standard research system based on the characteristics of the medicinal plant
A. argyi
and the processing characteristics of
A. argyi
decoction pieces in order to systematically explore the transformation rules before and after processing, and clearly explain the scientific connotation.