Construction and application of rational drug use database for children in our hospital

JIANG Zhiping; PENG Qian; WANG Fangjie; ZHOU Zhihong; HU Waiguang

doi:10.6039/j.issn.1001-0408.2023.08.21

您当前的位置：

首页 >

文章列表页 >

Construction and application of rational drug use database for children in our hospital

更新时间：2023-04-25

- Construction and application of rational drug use database for children in our hospital
- ZHONGGUO YAOFANG Vol. 34, Issue 8, Pages: 1005-1009(2023)
- 作者机构：
  
  湖南省儿童医院药学部，长沙　410007
- 作者简介：
- 基金信息：
- DOI：10.6039/j.issn.1001-0408.2023.08.21
  CLC： R95
- Published：30 April 2023，
  
  Received：08 November 2022，
  
  Revised：28 March 2023，
扫描看全文
蒋志平,彭骞,王方杰等.我院儿童合理用药数据库的构建与应用 ^Δ[J].中国药房,2023,34(08):1005-1009.

JIANG Zhiping,PENG Qian,WANG Fangjie,et al.Construction and application of rational drug use database for children in our hospital[J].ZHONGGUO YAOFANG,2023,34(08):1005-1009.
蒋志平,彭骞,王方杰等.我院儿童合理用药数据库的构建与应用 ^Δ[J].中国药房,2023,34(08):1005-1009. DOI： 10.6039/j.issn.1001-0408.2023.08.21.

JIANG Zhiping,PENG Qian,WANG Fangjie,et al.Construction and application of rational drug use database for children in our hospital[J].ZHONGGUO YAOFANG,2023,34(08):1005-1009. DOI： 10.6039/j.issn.1001-0408.2023.08.21.

摘要

目的

构建我院儿童合理用药数据库，为保障儿童用药安全提供参考。

方法

通过搭建知识库基本架构、制定儿童用药证据质量等级参考标准，提炼儿童用药循证证据，完成儿童合理用药知识库的构建与填充。从患者信息初步判定规则、药品基本信息规则、处方适宜性审核规则、结果标记及后处理规则四方面设计和构建儿童合理用药规则库。将数据库嵌入我院处方审核系统并上线应用，检验其效果。

结果

构建了1套包含672个儿科常用药品、15 000多条儿童合理用药规则的数据库。数据库应用后（2021年12月－2022年5月）的住院儿童不合理医嘱拦截率平均值为2.03%，高于数据库应用前（2021年6月－2021年11月）的0.80%（

＝5 784.389，

＜0.001）；经事后抽样和处方点评，数据库应用后的儿童出院病历用药医嘱平均合格率为99.10%，高于数据库应用前的94.58%（

＝301.237，

＜0.001）。

结论

基于循证证据自主构建的儿童合理用药数据库，贴近医疗机构儿科临床实际需求，能有效减少儿科临床不合理用药行为，提高处方合格率，保障儿童用药安全。

Abstract

OBJECTIVE

To establish a database of rational drug use for children in our hospital， and to provide reference for ensuring the safety of drug use in children.

METHODS

The construction and filling of the knowledge base of rational drug use for children were performed by establishing the basic structure of the knowledge base， formulating reference standards for the quality level of pediatric medication evidence， and refining evidence-based evidence of pediatric medication. The rule base of rational drug use for children was designed and built from four aspects： preliminary determination rules for patient information， basic drug information rules， prescription suitability review rules， result labeling and post-processing rules. The database was embedded into prescription review system of our hospital and was applied online to test its effectiveness.

RESULTS

A set of database containing 672 commonly used pediatric medicines and more than 15 000 rules for rational drug use for children was initially constructed. The average interception rate of unreasonable medical orders for hospitalized children after database application（from December 2021 to May 2022）was 2.03%， and was higher than 0.80% before database application（from June 2021 to November 2021）（

＝5 784.389，

＜0.001）； after post-sampling and prescription review， the average qualified rate of medication orders in discharged medical records for children after the application of the database was 99.10%， and was higher than 94.58% before the application of the database （

＝301.237，

＜0.001）.

CONCLUSIONS

Self-constructed evidence-based rational drug use database for children is close to the actual clinical needs of pediatrics in medical institutions， which can effectively reduce clinical irrational drug use behaviors in pediatrics， improve the pass rate of prescriptions， and ensure the safety of children’s drug use.

关键词

儿童合理用药数据库处方前置审核

Keywords

rational use of drugdatabasepre-prescribing review

references

General Office of National Health Commission of the People’s Republic of China. Notice on printing and distributing the management specifications for prescription review in medical institutions [EB/OL].（2018-06-29）[2022-10-26]. http：//www.nhc.gov.cn/cms-search/xxgk/getManuscriptXxgk.htm?idhttp://www.nhc.gov.cn/cms-search/xxgk/getManuscriptXxgk.htm?id＝de5c7c9116b547af819f825b5-3741173.

National Health Commission of the People’s Republic of China. Notice on further promoting the information construction of medical institutions with electronic medical records as the core[EB/OL].（2018-08-22）[2022-10-26]. http：//www.nhc.gov.cn/yzygj/s7659/201808/a924c19732-6440cdaaa0e563f5b111c2.shtmlhttp://www.nhc.gov.cn/yzygj/s7659/201808/a924c19732-6440cdaaa0e563f5b111c2.shtml.

General Office of State Department. Opinions on streng-thening the performance appraisal of tertiary public hospitals[EB/OL].（2019-01-16）[2022-10-26]. http：//www.gov.cn/zhengce/content/2019-01/30/content_5362266.htmhttp://www.gov.cn/zhengce/content/2019-01/30/content_5362266.htm.

General Office of National Health Commission of the People’s Republic of China. Notice on doing a good job in the assessment of rational drug use in medical institutions[EB/OL].（2019-12-18）[2022-10-26]. http：//www.nhc.gov.cn/yzygj/s7659/201912/5acbea335f5e458ba65a5-0c779aa62e8.shtmlhttp://www.nhc.gov.cn/yzygj/s7659/201912/5acbea335f5e458ba65a5-0c779aa62e8.shtml.

National Health Commission of the People’s Republic of China. Opinions on strengthening pharmaceutical affairs management in medical institutions and promoting rational drug use[EB/OL].（2020-02-21）[2022-10-26]. http：//www.nhc.gov.cn/yzygj/s7659/202002/ea3b96d1ac094c47-a1fc39cf00f3960e.shtmlhttp://www.nhc.gov.cn/yzygj/s7659/202002/ea3b96d1ac094c47-a1fc39cf00f3960e.shtml

蒋志平，彭骞，何莉梅，等. 儿科药品知识库和合理用药规则库的建立与探讨[J]. 中南药学，2020，18（6）：1076-1080.

张薇，许吉，邓宏勇. 国际医学证据分级与推荐体系发展及现状[J]. 中国循证医学杂志，2019，19（11）：1373-1378.

王雪韵，苏巍巍，丁宏，等. 我国儿童药品在临床使用中存在的问题及对策分析[J]. 中国药房，2019，30（2）：149-153.

梅枚，王立波，刘恩梅，等. 中国儿童超说明书用药管理现状及认知度的横断面调查[J]. 中国循证儿科杂志，2017，12（4）：289-294.

高璇，李智平. 236家医院儿科医务人员自身因素对儿童不良反应上报率影响的探讨[J]. 中国药学杂志，2015，50（2）：182-186.

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Cultivation of prescription-auditing pharmacists’ability in prescription pre-audit and case analysis

Optimization and practice in pre-review rules of traditional Chinese medicine prescription in medical institutions

Current Situation Analysis of Pre-prescription Review in Medical Institutions in China

Related Author

WANG Li

MA Yue

XU Ping

SHI Mili

YANG Chunsong

ZHANG Ting

GU Jie

DING Lanping

Related Institution

No data

Address：8/F,129 Daping Main Street,Yuzhong District,Chongqing 400042,P.R.China
Technical support is provided by Beijing Founder Electronics co., LTD 渝ICP备15012710号公网安备50010302001817
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰