Quality analysis of <italic style="font-style: italic">Codonopsis pilosula</italic> with different commodity specification grades

ZHANG Xiaohui; TONG Liguo; WANG Yibing; LI Zhiqiang; XI Xiaohu; WANG Shuang; WANG Shiwei

doi:10.6039/j.issn.1001-0408.2023.11.15

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Quality analysis of Codonopsis pilosula with different commodity specification grades

更新时间：2023-06-09

- Quality analysis of Codonopsis pilosula with different commodity specification grades
- ZHONGGUO YAOFANG Vol. 34, Issue 11, Pages: 1363-1367(2023)
- 作者机构：
  
  1.山西省中医药研究院中心实验室，太原　030012
  2.长治医学院药学系，山西长治　046013
  3.山西省中医院药剂科，太原　030012
- 作者简介：
- 基金信息：
- DOI：10.6039/j.issn.1001-0408.2023.11.15
  CLC： R917;R282
- Published：15 June 2023，
  
  Received：20 November 2022，
  
  Revised：03 January 2023，
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张小慧,仝立国,王亦冰等.不同商品规格等级党参药材的质量分析 ^Δ[J].中国药房,2023,34(11):1363-1367.

ZHANG Xiaohui,TONG Liguo,WANG Yibing,et al.Quality analysis of Codonopsis pilosula with different commodity specification grades[J].ZHONGGUO YAOFANG,2023,34(11):1363-1367.
张小慧,仝立国,王亦冰等.不同商品规格等级党参药材的质量分析 ^Δ[J].中国药房,2023,34(11):1363-1367. DOI： 10.6039/j.issn.1001-0408.2023.11.15.

ZHANG Xiaohui,TONG Liguo,WANG Yibing,et al.Quality analysis of Codonopsis pilosula with different commodity specification grades[J].ZHONGGUO YAOFANG,2023,34(11):1363-1367. DOI： 10.6039/j.issn.1001-0408.2023.11.15.

摘要

目的

研究不同商品规格等级党参药材的质量，为该药材的市场流通、科研及临床使用提供依据。

方法

根据目前党参药材的商品规格等级划分标准，收集不同产地、基原、商品规格等级的党参药材共17批，采用高效液相色谱法测定党参苷Ⅰ、党参炔苷和白术内酯Ⅲ的含量，采用《中国药典》（四部）中醇溶性浸出物测定法（通则2201）项下“热浸法”测定其醇溶性浸出物的含量，采用苯酚硫酸法测定其多糖的含量（以D-无水葡萄糖计）。

结果

对于党参的栽培品种，4种规格3个商品等级的党参药材均含有党参苷Ⅰ和党参炔苷，潞党参、纹党参还含有白术内酯Ⅲ。党参苷Ⅰ、党参炔苷、白术内酯Ⅲ含量方面，栽培药材二等品与一等品含量相当，甚至优于一等品，三等品含量低于一等品、二等品；两种野生党参中党参苷Ⅰ含量最高。醇溶性浸出物和多糖含量方面，栽培药材一等品含量高于二等品，二等品含量高于三等品，野生党参含量较低。

结论

不同商品规格等级的党参药材栽培品种的内在质量和目前依据性状和基原的规格等级划分标准基本一致，一等药材与二等药材均有较高的指标成分含量，属优质药材。

Abstract

OBJECTIVE

To study the quality of

Codonopsis pilosula

with different commodity specification grades， and to provide the data support for market transactions， scientific research and clinical use.

METHODS

According to the classification standard of commodity specification grades of

C. pilosula

， 17 batches of

C. pilosula

from different producing areas， origins and commodity specification grades were collected. The contents of tangshenoside Ⅰ， lobetyolin and atractylenolide Ⅲ were determined by HPLC. The contents of alcohol-soluble extracts were determined by hot dipping method stated in general rule 2201 of

Chinese Pharmacopeia

（part Ⅳ）. The contents of polysaccharide were determined by phenol-sulfuric acid method （calculated by D-glucose anhydrous）.

RESULTS

For cultivar of

C. pilosula

， four specifications and three commodity grades of

C. pilosula

all contained tangshenoside Ⅰ and lobetyolin； Radix

C. pilosula

from Shanxi of China and

C. pilosula

from Wenxian County of China， also contained atractylenolide Ⅲ. In terms of the contents of tangshenoside Ⅰ， lobetyolin and atractylenolide Ⅲ， the content of second class was equivalent to that of first class， even better than the first class， while the content of third class was lower than that of first class and second class； the content of tangshenoside Ⅰ was the highest among the two types of wild

C. pilosula

. The contents of alcohol-soluble extracts and polysaccharides in first class cultivated

C. pilosula

were higher than those of second class， and the second class was higher than the third class； wild

C. pilosula

had low content of alcohol-soluble extracts and polysaccharides.

CONCLUSIONS

The internal quality of

C. pilosula

is basically consistent with the classification standard of different commodity specification grades； the content of each indicator in first-class and second-class medicinal herb is high， making them high-quality medicinal herbs.

关键词

党参商品规格等级党参苷Ⅰ党参炔苷白术内酯Ⅲ多糖质量评价

Keywords

commodity specification gradetangshenoside Ⅰlobetyolinatractylenolide Ⅲpolysaccharidequality evaluation

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Quality analysis of Codonopsis pilosula with different commodity specification grades

DOI：10.6039/j.issn.1001-0408.2023.11.15

摘要

Abstract

关键词

Keywords

references