Clinical pharmaceutical practice of constructing mind map by clinical pharmacists for the consultation of pulmonary nocardiosis

DENG Tiying; HU Zhimin; XU Qing; ZHANG Shaohui; LI Lulu; GUO Heng; HU Lei; CHEN Fan

doi:10.6039/j.issn.1001-0408.2023.15.20

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Clinical pharmaceutical practice of constructing mind map by clinical pharmacists for the consultation of pulmonary nocardiosis

更新时间：2023-08-10

- Clinical pharmaceutical practice of constructing mind map by clinical pharmacists for the consultation of pulmonary nocardiosis
- ZHONGGUO YAOFANG Vol. 34, Issue 15, Pages: 1899-1903(2023)
- 作者机构：
  
  1.武汉市第一医院药学部临床药学室，武汉　430022
  2.武汉市第一医院检验科微生物室，武汉　430022
  3.武汉市第一医院呼吸内科，武汉　430022
- 作者简介：
- 基金信息：
- DOI：10.6039/j.issn.1001-0408.2023.15.20
  CLC： R95;R978
- Published：15 August 2023，
  
  Received：23 November 2022，
  
  Revised：01 April 2023，
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邓体瑛,胡志敏,徐清等.临床药师构建肺诺卡菌病会诊思维导图的临床药学实践 ^Δ[J].中国药房,2023,34(15):1899-1903.

DENG Tiying,HU Zhimin,XU Qing,et al.Clinical pharmaceutical practice of constructing mind map by clinical pharmacists for the consultation of pulmonary nocardiosis[J].ZHONGGUO YAOFANG,2023,34(15):1899-1903.
邓体瑛,胡志敏,徐清等.临床药师构建肺诺卡菌病会诊思维导图的临床药学实践 ^Δ[J].中国药房,2023,34(15):1899-1903. DOI： 10.6039/j.issn.1001-0408.2023.15.20.

DENG Tiying,HU Zhimin,XU Qing,et al.Clinical pharmaceutical practice of constructing mind map by clinical pharmacists for the consultation of pulmonary nocardiosis[J].ZHONGGUO YAOFANG,2023,34(15):1899-1903. DOI： 10.6039/j.issn.1001-0408.2023.15.20.

摘要

目的

探讨临床药师构建肺诺卡菌病会诊思维导图并应用于临床实践，为促进临床正确遴选诺卡菌病治疗用药并保障药物安全性及疗效提供参考。

方法

收集2017年1月－2022年4月我院肺诺卡菌感染患者7例，依据循证医学证据，针对诺卡菌菌种不同药敏性差异大和一线药物复方磺胺甲噁唑不良反应多的难点，构建会诊思维导图（主要包括了解病史、确定感染菌、明确危险因素、制定治疗方案、治疗评估等），制定7例肺诺卡菌感染患者的治疗方案，并进行全程药学监护。

结果

结合思维导图，根据诺卡菌菌种的不同、有无药敏结果、患者的过敏史等予以不同的抗菌药物联合方案，其中4例均联合了亚胺培南西司他丁治疗，对长期使用复方磺胺甲噁唑、利奈唑胺的患者进行全程药学监护，并及时处理了药物不良反应。

结论

临床药师将肺诺卡菌病会诊思维导图运用到住院患者治疗过程中，利用药学专业优势，参与临床药物治疗，在临床治疗团队中发挥了积极作用，促进了患者合理用药。

Abstract

OBJECTIVE

To explore the construction of mind map by clinical pharmacists for the consultation of pulmonary nocardiosis and its application in clinical practice， and to provide reference for promoting the correct selection of nocardiosis

treatment drugs in clinical practice and ensuring drug safety and efficacy.

METHODS

A total of 7 patients with

Nocardia

pulmonary infection from January 2017 to April 2022 in our hospital were collected. Based on evidence-based medicine， a consultation mind map （mainly including understanding the medical history， identifying infectious bacteria， identifying risk factors， developing treatment plans， and conducting evaluations） was constructed to address the difficulties of large differences in drug sensitivity among different strains of

Nocardia

and numerous adverse reactions of Compound sulfamethoxazole as a first-line drug. The treatment plan was developed for 7 patients with pulmonary nocardiosis， and whole-process pharmaceutical care was provided.

RESULTS

Combined with the mind map， different antibiotic combination regimens were given according to the drug sensitivity results of

Nocardia

， the different species of

Nocardia

， and the patient’s allergy history. Among them， 4 cases were treated with imipenem cilastatin， the patients receiving Compound sulfamethoxazole and linezolid for a long time were given full pharmaceutical care， and the adverse drug reactions were timely treated.

CONCLUSIONS

Clinical pharmacists apply the consultation mind map of pulmonary nocardiosis to the treatment of inpatients， take advantage of pharmacy， participate in clinical drug therapy， and really play a role in the clinical treatment team so as to promote rational drug use.

关键词

肺诺卡菌病临床药师思维导图药学实践会诊

Keywords

clinical pharmacistsmind mappharmacy practiceconsultation

references

HAMDI A M，FIDA M，DEML S M，et al. Retrospective analysis of antimicrobial susceptibility profiles of Nocardia species from a tertiary hospital and reference laboratory，2011 to 2017[J]. Antimicrob Agents Chemother，2020，64（3）：e01868-e01819.

HUANG L，CHEN X C，XU H P，et al. Clinical features，identification，antimicrobial resistance patterns of Nocardia species in China：2009-2017[J]. Diagn Microbiol Infect Dis，2019，94（2）：165-172.

PAIGE E K，SPELMAN D. Nocardiosis：7-year experience at an Australian tertiary hospital[J]. Intern Med J，2019，49（3）：373-379.

VALDEZATE S，GARRIDO N，CARRASCO G，et al. Resistance gene pool to co-trimoxazole in non-susceptible Nocardia strains[J]. Front Microbiol，2015，6：376.

张银利，高大泉，谢亚萍，等. 播散性诺卡菌病合并肺曲霉感染1例[J]. 中国感染与化疗杂志，2021，21（1）：93-95.

陈国敏，王东辰. 血培养检出皮疽诺卡菌1例[J]. 中国感染与化疗杂志，2021，21（2）：214-215.

彭书玲，诸兰艳. 支气管扩张患者合并肺诺卡菌病2例[J]. 中国感染与化疗杂志，2019，19（5）：565-567.

CLARK N M，REID G E，Infectious Diseases Community of Practice. Nocardia infections in solid organ transplantation[J]. Am J Transplant，2013，13（Suppl 4）：83-92.

TAN Y E，CHEN S C A，HALLIDAY C L. Antimicrobial susceptibility profiles and species distribution of medically relevant Nocardia species：results from a large tertiary laboratory in Australia[J]. J Glob Antimicrob Resist，2020，20：110-117.

KUCHIBIRO T，IKEDA T，NAKANISHI H，et al. First case report of pulmonary nocardiosis caused by Nocardia mexicana[J]. JMM Case Rep，2016，3（4）：e005054.

MAJEED A，MUSHTAQ A，ZANGENEH T，et al. Intractable cerebral Nocardia mexicana in a GvHD patient successfully treated with linezolid[J]. Bone Marrow Transplant，2017，52（10）：1476-1478.

李凤玉，邓静敏. 肺诺卡菌病诊治的研究进展[J/OL]. 中华临床医师杂志（电子版），2020，14（10）：848-852[2022-10-10].https：//kns.cnki.net/kcms2/article/abstract?v=3uoqIhG8C44YLTlOAiTRKibYlV5Vjs7iy_Rpms2pqwbFRRU-toUImHQVUg9qGgQ2vAkozf9mmGFL1WMwhtq9eUq-DFQjvLYZzO&uniplatform=NZKPThttps://kns.cnki.net/kcms2/article/abstract?v=3uoqIhG8C44YLTlOAiTRKibYlV5Vjs7iy_Rpms2pqwbFRRU-toUImHQVUg9qGgQ2vAkozf9mmGFL1WMwhtq9eUq-DFQjvLYZzO&uniplatform=NZKPT.

张淑香，钱玉婷. 诺卡菌感染9例临床分析[J]. 中国感染与化疗杂志，2017，17（4）：356-360.

李刚，程振娜，陶佳，等. 诺卡菌耐药性及氟喹诺酮类耐药相关基因研究[J]. 中国感染与化疗杂志，2018，18（2）：190-194.

张盛斌，朱红军，林茂煌，等. 肺诺卡菌病12例临床分析[J]. 中国感染与化疗杂志，2020，20（4）：401-405.

毛雅云，陈磊，翁恒. 肺诺卡菌病25例临床特征分析[J]. 中国感染与化疗杂志，2020，20（6）：613-617.

WEI M，WANG P，QU J X，et al. Identification and antimicrobial susceptibility of clinical Nocardia species in a tertiary hospital in China[J]. J Glob Antimicrob Resist，2017，11：183-187.

UHDE K B，PATHAK S，JrMCCULLUM I，et al. Antimicrobial-resistant Nocardia isolates，United States，1995-2004[J]. Clin Infect Dis，2010，51（12）：1445-1448.

KUROSAWA S，SEKIYA N，DOKI N，et al. The emergence of rare nocardiosis following allogeneic hemato- poietic stem cell transplantation in the era of molecular taxo- nomy[J]. Int J Infect Dis，2019，89：154-162.

SHOKRI D，MOTALEBIRAD T，JAFARINIA M，et al. First case report of pulmonary and cutaneous nocardiosis caused by Nocardia mexicana in Iran[J]. Access Microbiol，2019，1（4）：e000016.

程振娜，李刚，赵梅，等. 诺卡菌对β-内酰胺类药物耐药性及与其耐药相关基因关系研究[J]. 中国抗生素杂志，2021，46（11）：1054-1058.

叶晓芬，张捷青，金美玲. 临床药师对1例红斑狼疮合并诺卡菌感染治疗的药学监护：药物治疗中的“两点论”和“重点论”[J]. 上海医药，2020，41（21）：71-75.

严群锋，张琦，孙正林，等. 统一规范诺卡菌各菌种中文名称的提议[J]. 中华传染病杂志，2022，40（4）：246-247.

黄凌斐，杨巨飞，王慧娟，等. 思维导图在小儿用药专业临床药师培养中的应用研究[J]. 中国药学杂志，2018，53（10）：843-846.

冯雪梅，倪雯雯，王艳霞，等. 基于思维导图的医学功能学虚拟实验教学探究[J]. 实验室研究与探索，2022，41（7）：202-205.

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